Microtubules turn over rapidly

Microtubules turn over rapidly arc Kirschner recalls that the mid-1980s “was a very innovative time.” While the era was giving rise to stonewashed jeans and rap music, cell biology was entering new territory as it finally went molecular. For cell biologists who, like Kirschner, were interested in the cytoskeleton, there was an even more exciting possibility: the modification of interesting proteins to form reagents that could be used to follow dynamics inside of cells. Kirschner’s attention turned specifically to biotinylated tubulin. M